If you have evidence that a creator or game is doing something illegal or violating Itch's rules, you should report it using the button at the bottom of the game's page and send all the evidence to the staff.
If it's a copyright violation, the copyright holder is responsible for filing the report.
If you simply don't like the content, but the game doesn't violate any laws, Terms of Service, or copyright, then the staff will not delete the game.