Hi, you need to set it up as with most plugins.
The Self Refresh Only is pretty plug and play, but you can turn it OFF if you don't need it.
For the switches and variables that do not cause events to refresh, you need to enter in the switch / variable ids that you do not want to refresh the map.
The search limit is a simple number parameter, the lower the number the less intensive pathfinding will be (if set to 0, it will use default pathfinding length).
To skip event updates, you need to add the note tag to any event you want to skip updating.
To have it automatically add waits to your common events, you need to set that to true and set the wait frames you want. Higher wait frames will be less intensive on your game.
You can read more about all of the parameters on the wiki: https://caspergaming.miraheze.org/wiki/CGMZ_Anti_Lag
All of my plugins have a wiki page that details the full parameter list, plugin commands, and more (some sections not applicable, for example this plugin does not have any plugin commands).