Well this is pretty cool. Its very unique and is like playing a roguelike with really bad luck which is complemented by all the randomness in the items. I've only played the tutorial and one other run so I assume there's a fair bit I haven't seen yet, but I would like to see some way to remove items from your deck and some support for low universe runs; although if the goal is score rather than survival, low universe runs wouldn't work. First impressions are really good though.
High Score: 290.78
Edit: Yeah I see the low universe synergies now. Its a fun game and I wanna try many different strats. (also I think shuffle is really good)