Do you mean you would prefer the option to release burdens by clicking on the screen? Or do you mean to be able to use a mouse button other than left click or right click, rather than using the default number keys? If you want to change the controls I believe it is possible using the config window when opening the standalone download.
Oh cool! That would have been interesting to let the player unlock the mouse cursor and release burdens. I would add that option, but I’m not working on the old version. I’m working on a new demo for Enchain with revamped burden mechanics: Gameplay Preview