The bad luck does make it a frustrating experience at times, and we were okay with that. A lot of classic dungeon crawlers can be very punishing. Sometimes you'll have a good run and land all your hits for the first few encounters, other times you might miss five shots on the first enemy! But since the map stays the same you at least will always be able to rely on knowledge from a previous playthrough :)
Hints: Luck does not affect prayers, and when you get blessed your next attack or scream is guaranteed to hit! It can also grant you extra bullets or healing.
Screams are more effective at low health.
If you find yourself running out of ammo, try looking for more levers, there's a certain enemy in the game that drops something you may find useful!