The best party I've found with this mode so far is Arcanist, Charlotte, Hinaya, and Alice. You will mainly use Arcanist skill for damage, and Charlottes party skill as much as possible. It boosts 1d4 damage to high amounts because of Charlottes permanent +2 to 1d4 dice, plus Alice rolling up to 5 1d4 die based on your max mana, and Hinaya's chance to boost 1 of the 3 damage dice (d4, d8, or d12) by +3. By the end of the run, you'll have about +25 to +30 damage to 1d4 die, and since you roll somewhere around 20 dice per roll you one shot most enemies. If anyone has any other synergistic parties, let me know, I'm really enjoying this game mode.
Viewing post in Dungeon Master - Basic ability/character list
I haven't unlocked anything you mentioned except the Arcanist, yet - I'm excited to try this combo out, and add their abilities to The List™. My current mainstay is MC Druid (or whatever the Nature class is called, I don't remember if it's named properly), with Roxy, Anna, and Phoenix. Nature's Fortress just keeps building those dice, and all three die types are covered for heavy damage. d4 bonuses? Spam Anna's Fire Bolt. d8? Nature's Wrath, bby. d12? Let Phoenix go nuts. Choose Mana capacity/regen increases whenever possible, and watch the enemies fall to beeg numbers.
I'm actually rocking Defile, Samantha, Sofia, and Charlotte. Defiler and Sofia drop heal/shield/dmg dice at the start of every turn. Samantha throws two heal dice once 5 have been thrown, and Defiler throws heal dice once 10 have been thrown. Charlotte for her party skill and 1 mana stacking attack. Once you get higher mana and regen? You either take zero damage or it gets healed away in first round as Char nukes them. Heck, if you get a little bored of one shotting dudes you can just use Sofia's 3 mana attack since it just keeps getting better. I've had 370 shield in a single fight. NOTHING gets through most rounds. The healing passive from Sam and Defiler makes up for what damage does get through.