Like this one :
Viewing post in Rock Paper Scissor 0 player game comments
Maybe something with betting on top...
- player can bet on what he think will win
(difficulty of bets must of course somehow increase)
(going than full roguelite with an upgrade shop might than also be an option)
or you go in direction of simulation... instead of stone, paper, scissores you have different populations ... and the player can play around with some parameters to trigger indirect some evolution or something