Very creative idea! Unfortunately, despite trying my hardest, I couldn't go much beyond crossing the two laces. The fact that there are 20 DIFFERENT BUTTONS you need to use simultaneously just to move the two hands is simply too much for me. I felt like I was playing a video game for the first time, haha. Maybe if it was playable with a controller I could more easily wrap my head around it (you know, two analog sticks, two pairs of bumper/trigger buttons for up/down, d-pad and face buttons for 8 fingers total). But still, I feel it ends up being a bit overcomplicated. In QWOP for instance, you only have 4 buttons. So perhaps adapting a simpler control scheme will benefit the game.
Regardless, really cool submission! I'm sure some people with more patience will make really cool knots, it's just too hard for me :p.