I don't have a ton of details. I was doing my normal daily routine feeding my animals and going to the mine, and suddenly I couldn't interact with anything. Neither the left nor right mouse button worked. I wasn't using a mouse - I changed the left/right button hotkeys to F and G - but they weren't working at all. I tried everything I could think of - moving to a different area, interacting with different things. I also tried clicking with my laptop's trackpad. Nothing worked. I finally had to close the game and reopen it.