Destroyed the game in less than a minute with an auto-clicker, always counter that when you make an incremental (I don't want to hear the argument of not using one, this is part of Incremental gameplay)
For an full (non-jam) version, I would implement auto-clicking into the game itself, the player already ends up clicking other stuff anyway. Honestly, if a game becomes more fun with a third-party clicker, then the issue isn’t the cheat, it’s the design of the game.