Very clever little game! I appreciate the dual-consequence nature of getting the pickups, where you need to pick them up to stay alive but you also lose control and reaction time. With that being said, when I read your description, I was surprised to see that the number was also supposed to be score; I didn't necessarily feel like it was a number I wanted to get as high as possible, since you lose so much control and reaction time when you're moving so quickly. I would suggest maybe making lanes map directly to something like the ASD keys, so the player can react faster?
Good game, I think it has a lot of potential!