Dang, this looks REALLY GOOD. I like the feel of it - I am a sucker for hand-drawn games. Unfortunately, there are more than one room where I entered and Holmes couldn't move or disappeared entirely? This seems to be a known bug, and I'm so sorry you don't get to polish it during the jam. :c
Honestly, my favorite part of walking around was watching those little smoke bubbles trail him! Fantastic detail that I really, really enjoyed. All of the designs were great. :)