This is a really interesting idea! Agree with some other comments that a minimap would've been very helpful and maybe some visual signs that a corridor is meant to be a one way (I spent a little too long trying to swim upstream not even realising I was going the wrong way). I also didn't realise there were enemies already chasing me near the start of my playthrough and totally got jumpscared when I swung my camera around and saw like 10 germs chasing me lol. Great game! Sometimes the camera goes a little wonky but its not too bad.