I've started only 3 runs where I only have access to basic stuff that does nearly nothing but my opponent has something that stuffs mine with eggplants or milk and then I just can't do anything because I permanently have no space or my inventory is slowly overtaken by duplicating junk.
Seriously, the difference between good vials and bad vials is insane. If your opponent has something GOOD you just lose, it takes FOREVER to lose, and it hurts worse and worse the entire time.
The fact that this game is SO CLOSE to being great but manages to trip THIS HARD is painful. There needs to be counterplay in "card" games like these or else it just falls apart.