He's definitely different if you're talking about the Bear. Timing and pacing your attacks is a pretty good strategy. You can also go back and grind more xp to get a few more upgrades!
Which boss? The Bear can be easily dodged, and Josie can be easily avoided by jumping into the water, which is NOT poison/aphrodisiac. If Josie hits you, you have to stand up quickly, cause if she grabs you while you're down, it'll instantly take you to her CG, which counts as a Game Over.
