Yes, it is. It will make the battle to Warlord (Arihama) a bit easier and you will amass EXPERIENCE for your mc. Equipments will add to your mc stats, so you can kill the boss efficiently, Pills that can be hoarded from the through Galactic Union (GU) Missions. It will shorten the amount of times battling the Warlord, mitigating impacts of anyone dying from the same battle.
SPOILER some of the crew members will die. e.g. Hakkon (The Subguhnir Alpha, if you choose to hire him in Akra), Bradley (if you didn't gotten to the side quest) NPC: such as Riordan (can die too if you choose let him join in the battle).
NOTE: They will not, if you didn't make the battle for a longer amount of time. Or you choose to exclude them, like Rylan (due to his brother's wishes) or Hakkon.
Bradley's chance to die is from prolonging from the battle or not doing the side quest too.
(If you killed the Subguhnir Alpha at Akra, you cannot have him (Hakkon))