I love the theming on this, I can totally see the fleshy/corruption vibe. This does a very good job of hitting on the limitation, it feels like everything you do, whatever you do, seems to loose you life.
I wish the trade in shrines were more rewarding as well (Maybe even as high as like, +10?). It doesn't feel good to use one for two health, that you may have lost just by trying to interact with it. Also perhaps this is intentional, but I'm pretty sure the jump cost makes the game unplayable.
The star shape, is kind of brutal, though I suppose that's sort of the point XD. Putting a star picture on a rounded rectangle or something would be kinder to the player as far as collisions if that was something you wanted to do.
The atmospheric background audio is quite nice, and the story is a nice touch, and perfectly functional.