The game is written as GMless, but if you really want, you can surely tweak it to have someone facilitate it by playing most of the minor characters and help coordinate everyone. I recommend if you use a GM to still have everyone create a villain character and have the GM create one more as their leader.
This game doesn't have printable play materials yet, so you'll have to copy a whole bunch of stuff in the first session, so I recommend you go in knowing that first session will be "session 0" and you probably won't get much story going unless you play for a long time.
If you have any specific concerns, do let me know! Also tell me how the game goes if you do end up playing it~