There are many female bosses in this game. Well, to have access to information about your opponents, try to explore the game more actively: one of the artifacts will allow you to receive such information, and if you actively use it, it can become a skill for our blonde.
For demon generals, you need to come up with a strategy to drain their magical energy so that they can't regenerate their main energy. To do this, you need to have enough skills based on the use of clothing and artifacts. More details on this are in the Agranor library.