Under this formulation we can understand different events. For the last, at the moment, event strongly depends on your choice and on some of your earlier choices.
But the optimal moment for visiting Demenea's new home can be suggested by the fortune teller.
In my case, I simply finished all the story quests and then started looking for hidden quests one by one, periodically coming to the fortune teller. She told me that it was time to visit our horned beauty. Well, then : just a visit to her new home (Agranor) and a choice of action. And either you continue the friendship or not.