Beautiful presentation and a nice, visual novel approach to exploration and progression! This game's style reminds of the time I tried using RPG Maker 2003 to make a point and click as well (Justice and Inquiry), though you using a Maker with actual mouse control options helped it turn out much better than what I'd made!
The story became involving very quickly. Reimah is extremely likeable as a protagonist, especially with her beleaguered attitude and frustration with overwork. Seeing her story through was motivating enough for me to finish the surgery puzzle, which is the type of puzzle I'm usually too squeamish to look at.
I was concerned that the minimal amount of conventional gameplay elements would cause the game to become tiresome, but I actually became thankful for how it allowed the story to flow with minimal interruption. I do feel the game might benefit from some adventure game puzzles in the normal environment (like needing to have a proper sequence of events before progressing, such as dressing Reimah before she can leave or packing the meds into the briefcase herself), but I can see how that might lead to unfortunate "needle in a haystack" scenarios of clicking randomly in hopes of finding an obscure object. As it is, the point and click gameplay works well.
I enjoyed it as a visual novel with a relatable protagonist and fun yet gruesome twist!