I've been reworking episode 2, not sure when I'm gonna update it, but the death from above boss is one I wanted to test a bit more.
I think stuff that helps is knowing where medkits are because they stop the poisoning.
keep moving.
I think rapid fire weapons may be the best since the boss is hard to hit, though if you can land a rocket, it does a lot of damage, sometimes when it enters vents at ground level, it can't dodge the rockets.
the current version should have sound cues when the boss gets near so you can hear if it tries to sneak up on you. the 1st version didn't have those sounds and it made the boss melee attacks devastating.
the boss glows in the light, so use a flashlight
I think next update will nerf it in some ways. there is a big chance it breaks saves too since all levels are changed.