So yes, the latest patch I added in seeded rng though at least yet you can't change the seed yourself. How did you restart the run? I guess somehow it got stuck using the same seed...
Oh now I think what is happening. So when you get the key, it saves the seed for the next run. If you just refresh after that it doesn't reset the seed at that point. So if you're stuck in a limbo like that now, you can hit restart on options menu right after the page reload. Will fix this on the next patch too. Obviously it doesn't need to save the seed after it's been used.