These characters have hints to all the main quests. Therefore, if they are silent - you either started a quest that blocks the rest of the quests, or did not do something at the previous stages of the game, for example, do not develop skills and alchemical experience.
Such an effect can also be if you do not bring the training of available bodies (doll, elf, our hero) and our friends and girlfriends at work to the green level.