Its Completely RNG at the moment, with it being pretty unforgiving even as the Dev I have a hard time cause rnjesus is not my friend lol. It gets especially hard later on trying to remember what you've already tried or not. Later updates will include things to help with this as well as hinder. There will be, between acts, a choice sacrifice (a roguelike element where you choose one that will have a positive and negative effect) that will change the play style and make each run feel more unique as well as some quick time events to switch up the monotony.
Thank you so much for playing!