I'm not sure, but i think this is a max setup when you have everything unlocked, help me improve it if i'm wrong.
Edit:
I moved like 2 things and it made it slightly better.
and how the hell do you get some of these achievements? (atomic, scorched earth, factory, completionist, atlantis)
Edit2:
After over 2 hours, I think this is it, I still don't know how to get some of these achievements, but I think this is the MAX setup...
@UntrainedMonkey
One miniscule thing... Create a third hexagons, using a bit of rearranging, and put it in the middle of the bottom row