Played this yesterday in a 3 hour session. The players absolutely loved descending down a skeletton.
My tips for hosting this as a oneshot: Ask the players what evil cult they swore revenge on. Let them flavor the cult. Then change the cultists in-game accordingly. This adds some investment on the players' part, sets a clear goal (=take revenge), and it makes the scenario reusable for you. You'll always be surprised who the bad guys are this time.
(In my case, apart from resurrecting the Kill-Giant, the cult was all about eating donkeys. Thus I decided they didn't have high priests, but "head chefs". The prisoners were sewn in a donkey costume. It was great.)
Overall: Quest for the Murder Sword is an excellent dungeon that is easily adaptable to suit any needs. Also, it looks gorgeous.