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Top rated freefor macOS with Mouse support tagged Sci-fi (392 results)

392 results

Explore games for macOS with Mouse support tagged Sci-fi on itch.io. Science-fiction. Commonly including things like aliens, advanced technology, and settings of outer space or distant plan · Upload your games for macOS with Mouse support to itch.io to have them show up here.

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Alter genes, survive. Sci-fi RPG. 270k+
Rated 4.8 out of 5 stars
(469 total ratings)
Interactive Fiction
Play in browser
A lonely sea otter surviving in a world ravaged by the mysterious monsters known as the I.C.O.
Rated 4.9 out of 5 stars
(272 total ratings)
Visual Novel
I dared PewDiePie to dare me to make him a game in 14 days. This is the result.
Rated 4.8 out of 5 stars
(246 total ratings)
Adventure
A cyberpunk and solarpunk adventure-romance that explores a world where one side is forever day and the other, night.
Rated 4.8 out of 5 stars
(278 total ratings)
Visual Novel
A science fantasy romance adventure
Rated 4.9 out of 5 stars
(129 total ratings)
Visual Novel
Build a vast interstellar empire in 30 minutes flat.
Rated 4.6 out of 5 stars
(364 total ratings)
Strategy
Play in browser
Chronicles from 4.012 is a multi-choice otome game and visual novel, that takes place in a cyberpunk world.
Rated 4.8 out of 5 stars
(144 total ratings)
Visual Novel
The classic tale of cheese, goodwill and transdimensional fridge theft.
Rated 4.6 out of 5 stars
(299 total ratings)
Adventure
CAUTION: Escape from this supervillain at your own risk...
Rated 4.8 out of 5 stars
(102 total ratings)
Visual Novel
Tsundere Amnesiac AI x Pathetic Space Pirate
Rated 4.7 out of 5 stars
(180 total ratings)
Visual Novel
A sci-fi point & click adventure.
Rated 4.7 out of 5 stars
(144 total ratings)
Adventure
Play in browser
Gaslight eldritch horrors or die trying
Rated 4.7 out of 5 stars
(140 total ratings)
Visual Novel
you are a smart home ai.
Rated 4.8 out of 5 stars
(75 total ratings)
Interactive Fiction
A small game about greeting cards and life choices.
Rated 4.6 out of 5 stars
(134 total ratings)
Visual Novel
A twisted saturday morning cartoon adventure
Rated 4.6 out of 5 stars
(124 total ratings)
Adventure
The romance is flavored not only with drama and humor, but suspense, horror and fantastic entourage of characters.
Rated 4.7 out of 5 stars
(106 total ratings)
Visual Novel
Who are you? The voice in your head seems to know. NaNoRenO2019 [GxB,BxB,NBxB]
Rated 4.5 out of 5 stars
(237 total ratings)
Visual Novel
The world is ending, and you are still paying rent. A future history.
Rated 4.8 out of 5 stars
(41 total ratings)
Interactive Fiction
Play in browser
A remake of the text-only Super Star Trek but with the look & feel of Star Trek: 25th Anniversary
Rated 5.0 out of 5 stars
(23 total ratings)
Strategy
Play in browser
A sci-fi adventure reminiscent of 90s era Lucasarts.
Rated 4.6 out of 5 stars
(100 total ratings)
Adventure
A Wartime Garden Simulator
Rated 4.6 out of 5 stars
(112 total ratings)
Simulation
A small game about birds in space and killing time online.
Rated 4.7 out of 5 stars
(53 total ratings)
Visual Novel
A lowres metroidvania FPS, inspired by Metroid Prime
Rated 4.7 out of 5 stars
(50 total ratings)
Adventure
A LGBT-friendly cozy sci-fi cooking/dating sim about making friends, finding love, and running a diner in deep space
Rated 5.0 out of 5 stars
(20 total ratings)
Visual Novel
This world is a wasteland.
Rated 4.7 out of 5 stars
(48 total ratings)
Interactive Fiction
Play in browser
Explore a fallen utopia. Find your loved ones. Beware COSy.
Rated 4.8 out of 5 stars
(40 total ratings)
Visual Novel
A Cyber-Noir Visual Novel Adventure Game
Rated 4.9 out of 5 stars
(24 total ratings)
Visual Novel
Open Source Pixelart Sci-Fi Real Time Strategy Game
Rated 5.0 out of 5 stars
(15 total ratings)
Strategy
Creating an AI might have bittersweet consequences...
Rated 4.7 out of 5 stars
(42 total ratings)
Visual Novel
A mecha tactics game adapted from the Lancer TTRPG.
Rated 4.6 out of 5 stars
(87 total ratings)
Strategy
Play in browser
A base building game focused on economy and defence.
Rated 4.5 out of 5 stars
(131 total ratings)
Strategy
—Three different areas, three different decades, three different tales. A kinetic story anthology.
Rated 4.9 out of 5 stars
(19 total ratings)
Visual Novel
Use your point & click skills to find all the kids in a galaxy 39 light years away?
Rated 5.0 out of 5 stars
(13 total ratings)
Adventure
The prince has locked you in the maintenance room.
Rated 4.7 out of 5 stars
(34 total ratings)
Visual Novel
Play in browser
Sci-fi relationship simulation - can your space colony and your love survive?
Rated 4.6 out of 5 stars
(52 total ratings)
Visual Novel
A mystery sci-fi point & click adventure
Rated 4.7 out of 5 stars
(33 total ratings)
Adventure
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