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An otome game is a story based video game that is targeted towards the female market. Generally one of the goals, besides the main plot goal, is to develop a romantic relationship between the female player character and one of several male or female characters.

http://en.wikipedia.org/wiki/Otome_game

Either prominently containing or entirely themed around romance, this genre is typically focused on interpersonal romantic relationships between characters and the player.

Contains lesbian characters or plot lines, typically influenced by Japanese media and containing an anime style.