Topwith Mouse support tagged 2D and Sci-fi (1,036 results)
Explore games with Mouse support tagged 2D and Sci-fi on itch.io · Upload your games with Mouse support to itch.io to have them show up here.
New itch.io is now on YouTube!
Subscribe for game recommendations, clips, and more
CAUTION: Escape from this supervillain at your own risk...
Visual Novel
Chronicles from 4.012 is a multi-choice otome game and visual novel, that takes place in a cyberpunk world.
Visual Novel
Hard sci-fi, top-down space simulator, with every aspect backed up by real physics and science.
Simulation
Fight your way through biohacked monstrosities and stop their progress in this old school FPS
Action
An audio mystery set in a time loop. Record, rewind time and broadcast snippets of radio shows!
Interactive Fiction
Mini city builder on a small planet for the Ludum Dare 38 Compo.
Simulation
Play in browser
Someone sent you an odd program but you have to download enough RAM first
Simulation
Play in browser
Discover the world of Transistor, a sci-fi-themed action RPG from the creators of Bastion.
Action
Help Pippy the rabbit make friends...?
Visual Novel
Play in browser
A quirky RPG made in 72 hours about bringing a space station of aliens together to stop an evil virus...
A retro sci-fi comedy point and click adventure featuring the hapless Captain Disaster.
Adventure
Stellar Mess: The Princess Conundrum is the first chapter of a series of 2D retro point&click adventure games
Puzzle
single star fighter trying to save as many civilians as possible before they are overrun by a marauder armada.
Action
Explore endless pixel worlds in your ship and on foot, mine resources , complete missions and fight enemies.
Action
Turn-based strategy game where you can push enemies to deal extra damage.
Strategy
Play in browser
Loading more games...