Skip to main content

Indie game storeFree gamesFun gamesHorror games
Game developmentAssetsComics
SalesBundles
Jobs
TagsGame Engines

Top Card Gamefor macOS with Mouse support (330 results)

330 results

Explore Card Game games for macOS with Mouse support on itch.io. Featuring gameplay centered around the strategic use of cards, these games often involve building decks, managing resour · Upload your games for macOS with Mouse support to itch.io to have them show up here.

New itch.io is now on YouTube!

Subscribe for game recommendations, clips, and more

A turn-based, deck-building roguelite focused on dice combinations!
Card Game
Play in browser
A turn-based roguelike (alpha version)
Card Game
Play in browser
Turn your humble farm into a majestic kingdom in this tranquil, enchanting card-based city-building adventure
Strategy
Play in browser
You are the Social Democratic Party of Germany in 1928. Can you stop the Nazis from taking power?
Interactive Fiction
Play in browser
A thinky solitaire game
Puzzle
The inventory management roguelike! Collect rare items, organize your backpack, and vanquish your foes!
Role Playing
Play in browser
Destroy the invading titans from within. Roguelike deckbuilder.
Card Game
Play in browser
Stack monsters into delightful combos.
Strategy
Play in browser
Yugioh Constructed & Draft Simulator
Card Game
​An homage to Art Fight, draw your cards, summon characters from various artists and duel for your favourite team!​
Card Game
Play in browser
What would an omniscient creature do with all that knowledge? Well, host a trivia game, of course!
Puzzle
Play in browser
A survival horror/roguelite/dark decision-making card game hybrid where morality conflicts with survival.
Card Game
Play in browser
P.T. recreated with HyperCard
Card Game
A standalone 1-4 player remake of the Picture Poker minigame from the Nintendo DS game "New Super Mario Bros"
Card Game
An introspective deck-builder about friendship, travel, and collecting snacks.
Echodog GamesVerified Account
Card Game
Master over 100 dungeons and 3 worlds in this dungeon crawler card game.
Card Game
Roguelite card battles
Card Game
Simple 40-card solitaire with multiple game modes
Card Game
Play in browser
A roguelike tactical card game set after a technological apocalypse.
Sharkbomb StudiosVerified Account
Strategy
RPG + Card Game
Role Playing
Play in browser
Collect forbidden trading cards. Summon a demon. End the world.
Adventure
Space colony card sim. Survive, craft, build, defend, prosper!
Card Game
All seven Zachtronics solitaire games, updated with new 4K graphics, plus one brand new Tarot-themed solitaire variant.
ZachtronicsVerified Account
Card Game
Devil deckbuilder
Card Game
Play in browser
A city planning deck-building game!
Puzzle
A deadly card game
Card Game
Play in browser
Frost
$6.99
Survival solo Card game
Strategy
On a quest for revenge in the wild west, how you play the cards you're dealt determines your fate.
Chris WadeVerified Account
Card Game
Bitesized roguelike dungeon crawler. Face a relentless crawl through the card-based dungeons.
Card Game
NBA stopped, but we're just starting! Basketball Dream Team is a new basketball digital card game in the making.
Card Game
Freeborn is a visual novel adventure about messy old friendships, card battles, and psychological chaos. #ChoicesMatter
Visual Novel
A disobedient solitaire card game
Card Game
Play in browser
Poker-based puzzle crawler
Puzzle
Play in browser
Pyrene
$14.79
Deckbuilding roguelike with dungeon crawling mechanics
Card Game
Loading more games...
itch.io now on YouTube!