16 pixels by 16 pixels is a common resolution for assets matching a low-res pixel art aesthetic. Although the assets may not be specifically 16x16, they are designed to work in a graphical setting where objects are around that size.
A subgenre of the adventure game, point-and-click games typically involve interacting with background objects, talking to non-player characters, and using an item inventory to solve puzzles that allow the player to progress through the story.
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