Hi so after 60 days of not playing the game I dive back in to the game and finish my first run.
So still some probleme but the progression is much more nice. I have found 3 unbeatable enemy deck (one robot copy of your card each time you play a followers, one with only charge and first strike and one beast who destroy your deck each turn they play).
Edit: I just have a strange bug where the ia freeze and dont play any card. I just have to restart a new game.