I have the same problem. Everytime you load a save the game runs very slow (like 1fps). I also noticed that if you load the game it does not use the settings chosen in the options settings. For example if I chose to play music, the game does not play music after loading. So maybe the game ignores the options where the fps are also set and runs a very low fps setting for some reason. It is just a guess though.
Another unrelated Problem I have is when fighting: If I hover over the attack button or any of the skills (like fleeing etc) my mouse blinks and flickers and I need to click a lot of times until the action is selected. For the rest of the game the mouse works fine.