Basically what it says; when you get hit by something (I don't know the terms) that makes you have to move your cursor over your brain until you hit 100% to stay in the game, which makes those non-permanent areas gray-out and be unusable for an amount of time, the count-down on getting access to those again is the same rate regardless of 1x or 2x speed-up (rough measurement by observation).
Also had a soft-lock after that which made the bottom UI disappear and a menu for one of the nodules stay open with no Close button available that I had to force-quit the game from; pretty sure unrelated and no idea what could have contributed to it.