Pretty good stuff.
I wish there was an option to have a futa-free "good ending" at the end. That'd be my only complaint about the game (aside from the lack of BGM for most of the game). Still, the CGs were nice, and the tone was good. I liked the fact that the breast/ass expansion was permanent and part of the canon route. Games about magical girls, in general, are also very good civilization. It was exactly what it needed to be.
Also, one very tiny nitpick is that the clue for Lithium was the repetition of "FOUR" in the note, but it's ambiguous as to whether this is hinting at its chemical number being the fourth element in the sequence or the fourth digit in the sequence, since either assumption gives exactly one resultant answer, but both answers are different (the 6 and 3 switch places).