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Just replayed it and there's no new content story wise after the sex scene with Claire, but you have more interactions on her and the other two's day to day, so it's not nothing

Wait what? It was in the wall this whole time? I never saw i

So the thing is, before bringing in Nyx, you have to activate the portal, remember how it says you gotta look for clues inside that room? There are 3 gems laying around, that is the first order of colors you have to use to activate the portal.