Apologies, I have located and solved the issue myself. It seems that, despite showing the correct symbol, one of the wheels was not quite rotated to the right position.
A member registered Mar 13, 2017
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SPOILER WARNING
I've been greatly enjoying playing GNOG today, however, I unfortunately appear to have encountered a couple of progress blocking bugs. They both happened in my final level, LAB-0. The first time I attempted it, I somehow managed to release a lot of steam in the upper area, preventing me from interacting with the wheel to change the top symbol. The second time around, I did everything I could think of to progress, even checking a walkthrough after quite some time. As far as I can tell, everything looks exactly as it should, the only difference being that I can't seem to get the beam level all the way to max position. Any time I drag the lever it appears to snap back to a position that is not quite full (see attached gif).
Other than this I can't nothing seems to differ from the aforementioned walkthrough.