One of my attempts, it might be from older version, but the strategy is still viable and working - put challice (or any healing) in the first slot with 4/4 spihon, and upgrade it each 10 levels just to outscale enemy damage - 10% of this healing will put You in unkillable state. Then, put other weapons in every other slot, any weapon that strikes 2 times per turn (blood fang and frost gem have the best value), and dismantle blood blade onto them - doesn't matter what quality. Then, enjoy winning every fight with turbo dmg scaling :) 
Axji
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A member registered 35 days ago
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Great fun game! Played until floor 260 just to see what type is used for HP, might try later for some "record" :D
Fun fact - don't know if its on purpose - after banishing all items (by accident, R.I.P. my Chalices), I got Iron Swords, there is option to banish them as well, but... I got Iron Swords again :)