I've played with no obvious issues over the course of over a week, but it seems that that I run into a reproducible performance lag after using SOLIS's biomass automation upgrade. Unlocking it causes no problems, but actually enabling the auto-purchase option causes the game to start stuttering and freezing every few seconds, which gradually worsens until the page is reloaded, then it'll be fine for a little while before slowing again. It persists even after disabling the auto-purchase, or saving and reloading; it only stops after traveling to a new planet.
It might be connected to the Bitwarden password manager extension, but I have no idea how or why it's only triggered after using this automation feature. At some points, Firefox was warning about the extension slowing down the page, and the lag went away after disabling it.