I got to level 5 after killing the various blades in the lil blade room and opening a nearby cabinet and the screenshake (and column of light) just got worse and worse and wouldn't stop. I turned it off in settings and while that fixed the screenshake my camera no longer looked at the protagonist and the glowing light was still there. Going back to the lab did nothing to stop this.
EDIT: also one of the boss' vertical punches hit a pillar and it froze up. I couldn't attack its weak point and it wouldn't stop being stunned.
a couple of other things: I feel like most of the enemies attack a bit too slowly to be much of a threat. It might be worth upping a bit. Or maybe decreasing how quickly you regen health in combat too. The fact that every enemy drops stuff you can absorb and use to heal yourself means that unless you're fighting something that doesn't drop anything like the ghosts in the pump rooms, you'll probably be able to outheal pretty much everything.
I like the base framework you've got going here though! Looks cool.
Also do you think you could add transparency as a customization option?