itch.io

As long as ive been playing, yeah, it is possible to avoid sex with men, but it's kinda hard because you need money for rent and the ingame world is pretty much fucked up, but possible nontheless

I don't think I've seen any lesbian stuff in the game(well watching other women fuck might be lesbian, but would kind of be stretching for a tag), and the only trans thing is you can pick at the beginning having a background where you used to be a man. No futa stuff either. As the other guy mentioned you can pull a virgin run I guess, but it'd be hard.