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the more often Lona gives birth, from certain monsters, the more genetic mutations her offspring carry. Blood purity can be taken as statistics.

For example, having reached 100% of the Orkoid blood value, Lona could lose the ability to give birth to people. Or the skin color would change to greenish, which would lower their reputation and morale.

Fluid contamination like the Taimanin and note that there are references to these ninjas in the game!