No difference other than knowledge of story. Part 2 starts after the traumatic end of part 1 which explains the reason you start statless without needing to be stated (highly recommend playing the first one) haven't finished 2 yet but it's pretty easy to level stats, I recommend luck first since it affects pretty much all your other stat increases and it's free
Viewing post in Reboot Love (Part 2) (2.7.6) (NSFW +18) comments
The free section is 0.2.7 if i recall, you're missing most the game. While Amelie seems that way it's due to the (currently unexplained) past between the two. The big bad at the end of 1 is the big bad in 2 and yes without spoiling it you'd have to play it. And yes Genex is why I gave this one a try, this one is interesting but not as good