This is cool, I dig it!
I'm still getting hang of the new twist, but what I have played is solid. Actually when I was brainstorming I had considered a card game, but it didn't seem to go anywhere, so I was excited to see this.
Art-wise I wish the background matched the card aesthetic a bit closer. I like the pixelated sharp card illustrations and they look a little out of place against the soft painterly background art. That said, minor critique, overall cool.