In some situations, you'd choose to skip taking points to maximise score on the next round. For example, if you've got "+100", "/100" and "-10", it'd be a good idea to follow this sequence: "+100" (all numbers go red), "skip", "/100" (all numbers go yellow), "yellow". This will clear all yellow numbers (4 points each) and you'll get a x3 multiplier.
Thanks for your review! :D