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after that just go to the lab

where can i find the lab? or how can i unlock it? i have just unlocked the buffet if some hints about my progress are needed (PC is 118 kg)

The lab will be unlocked automatically when you reach a weight were the PC worries about becoming immobile.

so i will need to wait untill then to fatten Diane up?

Yes, to fatten Diane up you need the lab.