The game seems very inspired by Enter the Gungeon and Binding of Isaac. The concept is nice but the gameplay itself has some issues.
The shooting doesn't feel very good. The main weapon reminds me of Gungeon's fish gun. A big part of what makes that gun feel good is the "oomph" of the gun animation and the sound effect. That, combined with the projectile speed and the damage sound is what makes the gun feel good, so I think the gunplay would be greatly improved with some animation and sound design.
Animations for the enemies taking damage would also improve the feel of the game.
There is a bug where I can make grandma invincible by just keeping space hold down at everytime.
I only discovered that I could switch guns at the end of my playthrough. Maybe explain that in the beginning or have somewhere where the player can pickup a new gun and is taught how to change them.