This is a very strong start and I'm impressed.
The setting is interesting and I'm eager to learn more about the factions, cultures and technologies we hear about. I think the LOOM is a great way to give us information without breaking immersion and I felt it told us enough to get a general idea of the world and characters while still leaving more to be discovered in the main storyline. Ravy's Story Time segment has intriguing implications. I suspect he's directly manipulating the Jazz without using Jazztech. The digital appearance and the way it recreates the ancient Liosian past suggests it has some connection to the cyberspace mentioned in the opening. The 'breathing' hallway and possible connection to Kweythwehnto also left me curious. Overall, the worldbuilding is original and creative so I'm eager to see where you go with it.
The writing had a consistently high quality and the introduction quickly pulled me in. I know some might not like the cryptic opening, but I personally wouldn't change anything. It's an effective way to get us invested in the mystery of what happened to the ancient Liosians, what their technology was like and how the opening narration is connected to the rest of the story. Bonus points for the clue in binary and the initial LOOM screen, I enjoyed these subtle hints. The character interactions and pace of the story were on point and kept me wanting more.
I loved the music and how well each track fit the mood of each scene. I like the sprites for the most part and the CG and background art are gorgeous. The UI was aesthetically pleasing and complements the theme of the game. You've already added image and music galleries which I appreciate.
As for possible improvements, I think there were some missed opportunities for CGs like during the rooftop embrace or the skydiving scene so I'd suggest adding a few more CGs to make the game more immersive. You've made good use of backgrounds for this but for some scenes I think it'd be better to see characters interacting with each other and the environment and for that a CG is better. Speaking of backgrounds, you might want to include them in the gallery alongside the CGs. Another thing, it would be better if the LOOM had an indicator showing which information was updated. I also think the posing of Kavir's hunched sprites looked a bit awkward and uncomfortable but perhaps that's just because they're meant to depict motion instead of being static. Overall, there's not much to improve so you're doing a fantastic job so far.