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Arack build is REALLY hard to get off the ground (I ended up using mayday on boss 1 just so he wouldn't kill me), but if you manage to get a few of them their exponential damage scaling means you can pretty much nuke bosses 6-12 instantly. 

This is good enough on its own, but really explodes if you can also throw a thief and game developer on top of this.

* Thief steals arack base damage and sets it to 0

* Game dev adds bonus damage to arack
* webs multiply bonus damage instead of the just the 1 base damage